Sharp Mesa Vista Clinical Research Center
Sharp Mesa Vista Depression Clinical Trials
Discovering new ways to treat depression.
At Sharp, we understand the toll that depression takes on your life — trouble sleeping, poor concentration, changes in appetite and lack of energy. If you find that you relate to these symptoms, we welcome you to participate in one of our research studies at Sharp Mesa Vista Hospital.
To enroll in a study, you must be:
- Between ages 18 and 64
- Diagnosed with depression
- In good general health
How it works: treatment-resistant depression clinical trial.
This study will compare the effects, both good and bad, of switching from a current, ineffective antidepression treatment to an esketamine nasal spray and oral antidepressant. The study is randomized and double-blind, meaning both the participant and the tester are unaware which group is receiving the experimental and placebo treatments. This is an active-control trial, so those in the placebo group will continue to receive an established therapy. The trial is being run at multiple centers throughout the country.
How it works: major depression treatment response clinical trial.
This study does not involve medication or a placebo and is open to adults over 18. A one-time blood sample will be collected with the goal of looking at genetic alterations to help scientists at Sanford Burnham Presby Medical Discovery Institute to discover the best individualized antidepressant treatment.
Candidates must meet the following:
- Nonresponsive to antidepressant treatment
- Nonresponsive to one antidpressant, but responsive to another
- Nonresponsive to more than one antidepressant, but responsive to another
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