Parkinson's Drugs Linked to Behavior Problems in Study
Hypersexuality, addictive gambling, binge eating noted with use of dopamine agonists
TUESDAY, March 29 (HealthDay News) -- Parkinson's disease drugs called dopamine agonists appear to cause impulse control problems in almost one-quarter of patients, says a new study.
Previous research has linked dopamine agonists, which include Mirapex (pramipexole) and Requip (ropinirole), to impulse control disorders, such as gambling addiction and hypersexuality, and to compulsive behaviors, such as binge eating, overspending and excessive computer use.
In this study, Mayo Clinic researchers analyzed Parkinson's disease patient records over two years.
"What we found was that as many as 22 percent of patients during that two-year period had a new-onset impulse control disorder," lead investigator and neurology fellow Dr. Anhar Hassan said in a Mayo Clinic news release.
The higher the dose of dopamine agonist, the more likely a patient was to develop an impulse control disorder, the researchers found.
"One in four patients who were on a medium therapeutic dose of the medication had an impulse control disorder. For patients who were taking a higher range of the medication, about one in three developed an impulse control disorder," Hassan said.
The study was recently published online in the journal Parkinsonism and Related Disorders.
Patients taking dopamine agonists and their families need to watch for any behavior changes, Hassan said. Reducing the dose or going off the medication usually resolves behavior problems within a few days to a month.
We Move has more about drugs used to treat Parkinson's disease.Robert Preidt SOURCE: Mayo Clinic, news release, March 23, 2011 Related Articles
- FDA Approves Hard-to-Abuse Narcotic Painkiller
July 24, 2014
- Gene Discoveries Could Shed New Light on Schizophrenia
July 22, 2014
Learn More About Sharp
Sharp HealthCare is San Diego's health care leader with seven hospitals, two medical groups and a health plan. Learn more about our San Diego hospitals, choose a Sharp-affiliated San Diego doctor or browse our comprehensive medical services.
Copyright © 2011 HealthDay. All rights reserved.