Ferriprox Approved to Treat 'Iron Overload'
A potential problem among people who get frequent blood transfusions
FRIDAY, Oct. 14 (HealthDay News) -- Ferriprox (deferiprone) has been approved by the U.S. Food and Drug Administration to treat excess blood iron among people who require frequent transfusions.
People with the genetic blood disorder thalessemia have an insufficient supply of hemoglobin, the protein that helps deliver oxygenated blood throughout the body. They often need frequent blood transfusions, which may lead to a buildup of iron in the blood (iron overload). People with thalessemia also are at greater-than-average risk of developing liver disease, diabetes, arthritis, heart failure or an abnormal heart rhythm, the FDA said in a news release.
Ferriprox has been approved for use in cases where other methods to remove excess iron are insufficient, the agency said.
In clinical testing of the drug, the most common side effects noted were nausea, vomiting, abdominal and joint pain, discolored urine, a potentially deadly decrease in infection-fighting white blood cells, and an increase in a liver enzyme that may indicate tissue or liver damage.
As a condition of approval, the Toronto-based drug maker ApoPharma must study the use of Ferriprox among people with iron overload who also have sickle cell disease, the FDA said.
The U.S. Centers for Disease Control and Prevention has more about iron overload.Scott Roberts Related Articles
- Eye Pigment May Help Vision in Hazy Conditions
August 28, 2014
- Scientists Spot Genetic Clues to Crohn's Disease
August 27, 2014
Learn More About Sharp
Sharp HealthCare is San Diego's health care leader with seven hospitals, two medical groups and a health plan. Learn more about our San Diego hospitals, choose a Sharp-affiliated San Diego doctor or browse our comprehensive medical services.
Copyright © 2011 HealthDay. All rights reserved.