COVID-19 information: vaccines, testing, getting care and more
Doctor's office
Enter your doctor's name to get office information.
Find labs in your network
Enter your primary care doctor's name to find labs in your network.
Find urgent care centers in your network
Enter your primary care doctor's name to find urgent care centers in your network.
Verify your medical group

Refer to your insurance card or call your insurance provider to determine your medical group.

You can also search for your primary care doctor to find the medical group you and your doctor belong to.

Driving Directions
Update Information
Forgot Password

Please enter your e-mail address.

Sharp Health News

What you need to know about 3 new COVID-19 vaccines

Jan. 27, 2021

Coronavirus, COVID-19 vaccine transparent liquid vials in the laboratory.
In December, many in the U.S. were thrilled to learn that the U.S. Food and Drug Administration (FDA) granted emergency use authorization for two COVID-19 vaccines, giving hope that the pandemic might soon be under control. One vaccine was created by biopharmaceutical company Moderna and the other by Pfizer, Inc.

Unfortunately, vaccination rollout has been slow across the country, and both the Pfizer and Moderna vaccines are currently in limited supply. However, the potential for additional vaccines to receive FDA emergency use authorization in the near future should mean that more vaccine doses will become available and more people can be vaccinated.

According to the Centers for Disease Control and Prevention (CDC), phase 3 clinical trials are in progress or being planned for three more COVID-19 vaccines:
How the new vaccines work
Unlike the Moderna and Pfizer vaccines, the three new vaccines are not messenger RNA (mRNA) vaccines - a new type of vaccine that uses genetic material from the virus that causes COVID-19 to give the body instructions for how to make copies of the spike protein unique to the virus. Recognizing that the protein should not be there, the body creates protective antibodies that will remember how to fight the virus in case of future infection.

Adenovirus viral vector vaccines
Both the University of Oxford/AstraZeneca and Johnson & Johnson/Janssen COVID-19 vaccines are adenovirus viral vector vaccines. These vaccines use adenovirus - a harmless common cold virus - that has been altered to deliver a piece of genetic code to our cells to mimic coronavirus infection. The cells make the surface spike protein of the coronavirus and then the immune system responds, priming it to attack any future coronavirus infection.

The Oxford/AstraZaneca vaccine requires two doses given four weeks apart, and the Johnson & Johnson/Janssen vaccine will only require one dose. The CDC reports that viral vector technology was used in Ebola vaccines and several studies of vaccines to combat other infectious diseases, such as Zika, the flu and HIV.

Protein subunit vaccine
Novavax's COVID-19 vaccine is a protein subunit vaccine. This type of vaccine combines a boosting agent with a component (subunit) from the spike protein in the coronavirus that causes COVID-19. When the vaccine enters the body, an immune response to the spike protein is triggered and antibodies are created to fight future infection.

Protein subunit vaccines are known for their effectiveness and used to prevent hepatitis B, flu and HPV. The Norovax vaccine will be given in two doses, 21 days apart.

Neither viral vector nor protein subunit vaccines require the cold storage temperatures that the two mRNA vaccines require. This might make the new vaccines appealing to small hospitals and health care providers in rural communities that may not have the proper equipment needed to store the Pfizer and Moderna vaccines already in use.

Importance of vaccination combined with precautions
Regardless of which vaccine people end up receiving, it is important to note that all vaccines given FDA emergency use authorization will be safe and effective at preventing COVID-19. What's more, neither of the two vaccines currently in use, nor the new vaccines in phase 3 trials, can cause people to become sick with COVID-19. All vaccines carry the risk of mild to moderate side effects.

Experts stress that vaccinating a majority of the population combined with the precautions we are already taking to slow the spread of COVID-19 is key to stopping the pandemic. So, even after vaccination, people are encouraged to continue to wear a face mask, keep a safe social distance, avoid large crowds and frequently wash their hands.

Get COVID-19 information and access to resources from Sharp HealthCare.

You might also like:

Choose the doctor who's right for you.

At Sharp, we make it easy to find an exceptional doctor — right where you live and work.

All Categories
Contact Sharp HealthCare
Call us


For medical or psychiatric emergencies, call 911 immediately.

Email us

Please do not use this form to convey personal or medical information.

How would you like to be contacted?
Date of birth

Find other numbers

View our phone directory

What's This?

These important numbers are located on your billing statement.

Find your Sharp Rees-Stealy account number

Find your SharpCare account number

Find your SharpCare account number
What's GDPR?

The General Data Protection Regulation (GDPR) governs the processing of personal information gathered from individuals while they are in the European Union (EU) and parts of the EEA (European Economic Area, which currently includes Iceland, Lichtenstein and Norway).

We are sorry, but we are unable to process your price estimate if you live or are travelling within the EU or affiliated nations.

What's This?

Many surgery and procedure names sound similar. If possible, please provide the current procedure terminology (CPT) code, which can be found on the order from your doctor.

If you cannot provide the CPT code, please contact your doctor's office for the CPT or a detailed description of services.